...The skin contains sebaceous glands, which have receptors, like most organs and cells in the body. Just as the muscle cells respond to steroids by growing, the sebaceous glands respond to steroids (particularly the androgen Dihydrotestosterone which the body produces as a byproduct of increased testosterone) with increased secretion. Just as the teenager with high testosterone levels suffers from acne, the 40-year old man with artificially high testosterone levels will suffer from acne for the same reason. The higher the dose, the higher the testosterone level in the body, which results in worse cases of acne. ...»
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«...Topical antimicrobial agents are effective in the treatment of inflammatory disease. Benzoyl peroxide is a bactericide and is an excellent first-line medication. The response to this agent is rapid, with improvement noted as early as five days after treatment has begun, but irritation is common. Water-based products, as compared with alcohol based products, when used at low peroxide concentrations (5 to 5 percent) will help to limit this problem and have an efficacy similar to that of other products in this class. Benzoyl peroxide does not induce resistance; when used with topical or oral antibiotics, it protects against the development of this problem....»
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